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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
Postnatal

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hand2  heart and neural crest derivatives expressed 2   (Synonyms: bHLHa26, dHAND, Ehand2, Hed, Thing2)
Results  Reference
1*J:81037 Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K, Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis. Cell Tissue Res. 2002 Nov;310(2):201-12
1J:135127 D'Autreaux F, Morikawa Y, Cserjesi P, Gershon MD, Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia. Development. 2007 Jun;134(12):2237-49
1J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38
1J:178308 Lei J, Howard MJ, Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis. Development. 2011 Nov;138(21):4789-800
1J:146634 Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, Martinelli DC, Fan CM, Peterkova R, Lesot H, Yoder BK, Sharpe PT, Primary cilia regulate Shh activity in the control of molar tooth number. Development. 2009 Mar;136(6):897-903
1J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23
1J:208894 VanDusen NJ, Vincentz JW, Firulli BA, Howard MJ, Rubart M, Firulli AB, Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Dev Biol. 2014 Apr 15;388(2):149-58

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory